Kolloquiumsvortrag: Prof. Dr. Nan Ma, Biomaterialforschung HZG / FU Berlin/ 27.04.2015

27.04.2015 von 17:15 bis 18:45

Institut für Materialwissenschaft, Kaiserstr. 2, Geb.C , Raum "Aquarium"

Titel: Stem cell and cardiac repair

 

 

Abstract:

 

Stem cell mediated therapies offer great regenerative potential to improve cardiac function and neovascularization in patients with cardiovascular disorder. Recently, numerous clinical and preclinical studies using different type of stem (progenitor) cells have demonstrated their promising therapeutic effect. However, the low rate of cell engraftment and survival in the ischemic tissue greatly limits their therapeutic efficacy. To achieve the maximal clinical benefits, Dr. Nan Ma and her team attempted to explore cell pre-selection, genetic enhancement, tissue engineering and protein and/or small molecule treatment approaches to further augment cell homing, engraftment and cell survival. In this presentation, Dr. Nan Ma will introduce you how to employ the novel cell-enhancement strategies to aid the stem cell treatment of ischemic heart disease. The presentation will also highlight the potential of applying genetic and chemical modulation to enhance stem cell therapeutic and latest progress on gaining mechanistic insights of stem cell-extracellular matrix interactions. Further, using Laser-Induced-Forward-Transfer (LIFT) cell printing techniques, we are able to produce functional cardiac patch. LIFT-based stem cell cardiac patches for the treatment of myocardial infarction might improve wound healing and functional preservation.

Prof. Selhuber-Unkel

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